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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HIRA
All Species:
45.45
Human Site:
T272
Identified Species:
62.5
UniProt:
P54198
Number Species:
16
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P54198
NP_003316.3
1017
111835
T272
V
G
H
R
K
A
V
T
V
V
K
F
N
P
K
Chimpanzee
Pan troglodytes
XP_001165585
1017
111787
T272
V
G
H
R
K
A
V
T
V
V
K
F
N
P
K
Rhesus Macaque
Macaca mulatta
XP_001112873
1138
124408
T392
V
G
H
R
K
A
V
T
V
V
K
F
N
P
K
Dog
Lupus familis
XP_543550
1017
111618
T272
V
G
H
R
K
A
V
T
V
V
K
F
N
P
K
Cat
Felis silvestris
Mouse
Mus musculus
Q61666
1015
111748
T272
V
G
H
R
K
A
V
T
V
V
K
F
N
P
K
Rat
Rattus norvegicus
NP_001129232
1015
111665
T272
V
G
H
R
K
A
V
T
V
V
K
F
N
P
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P79987
1019
112055
T272
V
G
H
R
K
A
V
T
V
V
K
F
N
P
K
Frog
Xenopus laevis
Q8QFR2
1013
112021
T272
V
G
H
R
K
A
V
T
V
V
K
F
N
P
K
Zebra Danio
Brachydanio rerio
XP_696478
1010
111223
T272
V
G
H
R
K
A
V
T
V
V
K
F
N
P
K
Tiger Blowfish
Takifugu rubipres
O42611
1025
111838
T272
V
G
H
R
K
A
V
T
V
V
K
F
N
P
K
Fruit Fly
Dros. melanogaster
O17468
1047
113397
T270
V
G
H
R
K
A
V
T
C
V
R
F
H
N
S
Honey Bee
Apis mellifera
XP_001122939
838
91355
A121
I
E
T
W
R
C
I
A
T
L
R
S
H
E
A
Nematode Worm
Caenorhab. elegans
Q09589
935
103412
F218
V
K
S
V
T
E
P
F
E
S
N
I
E
E
T
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q32SG6
964
105548
E247
R
H
S
A
P
V
L
E
R
G
E
W
A
A
T
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LXN4
1051
115544
I258
L
G
H
S
A
P
I
I
V
V
R
F
N
H
S
Baker's Yeast
Sacchar. cerevisiae
P32479
840
93871
E123
P
A
F
G
S
E
H
E
R
E
H
W
T
V
R
Red Bread Mold
Neurospora crassa
Q7RZI0
1035
112420
S272
I
E
R
T
G
W
D
S
E
I
N
L
I
G
H
Conservation
Percent
Protein Identity:
100
99.9
88.4
96.5
N.A.
95.7
95.5
N.A.
N.A.
86
78
69.8
67.7
31.1
40
26.5
N.A.
Protein Similarity:
100
99.9
88.9
98
N.A.
97.5
97.7
N.A.
N.A.
93.1
88.5
83.2
81.3
48
55.1
46.1
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
100
100
100
100
66.6
0
6.6
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
100
100
100
100
80
40
6.6
N.A.
Percent
Protein Identity:
N.A.
25.6
N.A.
25
22.4
25.9
Protein Similarity:
N.A.
43.7
N.A.
43.3
41.2
45.8
P-Site Identity:
N.A.
0
N.A.
40
0
0
P-Site Similarity:
N.A.
20
N.A.
60
13.3
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
6
0
6
6
65
0
6
0
0
0
0
6
6
6
% A
% Cys:
0
0
0
0
0
6
0
0
6
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
6
0
0
0
0
0
0
0
0
% D
% Glu:
0
12
0
0
0
12
0
12
12
6
6
0
6
12
0
% E
% Phe:
0
0
6
0
0
0
0
6
0
0
0
71
0
0
0
% F
% Gly:
0
71
0
6
6
0
0
0
0
6
0
0
0
6
0
% G
% His:
0
6
71
0
0
0
6
0
0
0
6
0
12
6
6
% H
% Ile:
12
0
0
0
0
0
12
6
0
6
0
6
6
0
0
% I
% Lys:
0
6
0
0
65
0
0
0
0
0
59
0
0
0
59
% K
% Leu:
6
0
0
0
0
0
6
0
0
6
0
6
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
12
0
65
6
0
% N
% Pro:
6
0
0
0
6
6
6
0
0
0
0
0
0
59
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
6
0
6
65
6
0
0
0
12
0
18
0
0
0
6
% R
% Ser:
0
0
12
6
6
0
0
6
0
6
0
6
0
0
12
% S
% Thr:
0
0
6
6
6
0
0
65
6
0
0
0
6
0
12
% T
% Val:
71
0
0
6
0
6
65
0
65
71
0
0
0
6
0
% V
% Trp:
0
0
0
6
0
6
0
0
0
0
0
12
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _